Product Name:Calcium Carbonate Tablets
Product Description:

Calcium carbonate tablets








Calcium carbonate tablets 500


Calcium carbonate is a dietary supplement used when the amount of calcium taken in the diet is not enough. Calcium is needed by the body for healthy bones, muscles, nervous system, and heart. Calcium carbonate also is used as an antacid to relieve heartburn, acid indigestion, and upset stomach. It is available with or without a prescription.


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This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.


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Dosage Forms


Oral:


Calcium: 1250 mg (elemental calcium 500 mg) [DSC]


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Pharmacologic Category


Antacid


Antidote


Calcium Salt


Electrolyte Supplement, Oral


Phosphate Binder


Pharmacology


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As dietary supplement, used to prevent or treat negative calcium balance; in osteoporosis, it helps to prevent or decrease the rate of bone loss. Calcium is an integral component of the skeleton and also moderates nerve and muscle performance and allows normal cardiac function. Also used to treat hyperphosphatemia in patients with chronic kidney disease by combining with dietary phosphate to form insoluble calcium phosphate, which is excreted in feces. Calcium salts as antacids neutralize gastric acidity resulting in increased gastric and duodenal bulb pH; they additionally inhibit proteolytic activity of pepsin if the pH is increased >4 and increase lower esophageal sphincter tone (IOM, 2011).


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Absorption


Minimal unless chronic, high doses; absorption predominantly in the duodenum and dependent on calcitriol and vitamin D; mean absorption of calcium intake varies with age (infants 60%, prepubertal children 28%, pubertal children 34%, adults 25%); during pregnancy, calcium absorption doubles; calcium is absorbed in soluble, ionized form; solubility of calcium is increased in an acid environment (IOM 2011); decreased absorption occurs in patients with achlorhydria, renal osteodystrophy, steatorrhea, or uremia


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Distribution


Primarily in bones, teeth (IOM, 2011)


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Excretion


Primarily feces (75%; as unabsorbed calcium); urine (22%) (IOM, 2011)


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Protein Binding


~40%, primarily to albumin (Wills 1971)


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Use: Labeled Indications


Antacid: For the relief of acid indigestion, heartburn, sour stomach, and GI upset associated with these symptoms


Calcium supplementation: For use as a dietary supplement when calcium intake may be inadequate (eg, osteoporosis, osteomalacia, hypocalcemic rickets) (IOM, 2011)


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Use: Unlabeled


Hyperphosphatemia in chronic kidney disease


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Contraindications


Hypersensitivity to any component of the formulation


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Dosage


Oral (dosage is in terms of calcium carbonate, except where noted; calcium carbonate generally provides approximately 40% elemental calcium):


Dietary Reference Intake for Calcium:


0 to <6 months: Adequate intake: 200 mg elemental calcium daily


6 to 12 months: Adequate intake: 260 mg elemental calcium daily


1 to 3 years: RDA: 700 mg elemental calcium daily


4 to 8 years: RDA: 1,000 mg elemental calcium daily


9 to 18 years: RDA: 1,300 mg elemental calcium daily


Adults, Females/Males: RDA:


19 to 50 years: 1,000 mg elemental calcium daily


≥51 years, females: 1,200 mg elemental calcium daily


51 to 70 years, males: 1,000 mg elemental calcium daily


>70 years, males: 1,200 mg elemental calcium daily


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Females: Pregnancy/Lactating: RDA: Requirements are the same as in nonpregnant or nonlactating females (IOM 2011).


Antacid:


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Children 2 to 5 years (10.9 to 21.3 kg): 375 to 400 mg as symptoms occur; maximum: 1,500 mg daily for up to 2 weeks; OTC dosing recommendations may vary by product and/or manufacturer; specific product labeling should be consulted.


Children 6 to 11 years (≥21.8 kg): 750 to 800 mg as symptoms occur; maximum: 3,000 mg daily for up to 2 weeks; OTC dosing recommendations may vary by product and/or manufacturer; specific product labeling should be consulted.


Children ≥12 years and Adolescents: 500 to 3,000 mg as symptoms occur for up to 2 weeks; maximum daily dose: 7,500 mg/day; OTC dosing recommendations may vary by product and/or manufacturer; specific product labeling should be consulted.


Adults: Generally, 1 to 4 tablets as symptoms occur; maximum: 8,000 mg daily for up to 2 weeks; OTC dosing recommendations may vary by product and/or manufacturer; specific product labeling should be consulted.


Calcium supplementation:


Children 2 to 4 years: 750 mg twice daily


Children ≥4 years and Adolescents: 750 mg 3 times daily


Adults: 500 mg to 4 g daily in 1 to 3 divided doses; OTC dosing recommendations may vary by product and/or manufacturer; specific product labeling should be consulted.


Hyperphosphatemia in chronic kidney disease (off-label use): Adults: Total dose of elemental calcium (including dietary sources and calcium-based phosphate binders) should not exceed 2,000 mg daily (Eknoyan 2003).


Dosing adjustment in renal impairment: CrCl <25 mL/minute: Dosage adjustments may be necessary depending on the serum calcium levels


Dosing adjustment in hepatic impairment: There are no dosage adjustments provided in the manufacturer's labeling (has not been studied).


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Administration


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Oral: Administer with food.


Capsules may be swallowed whole or opened and the contents mixed with food or drink.


Dietary Considerations


Take with food. Limit intake of bran, foods high in oxalates, or whole grain cereals which may decrease calcium absorption.


Some products may contain phenylalanine and/or sodium.


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Storage


Store between 15°C to 30°C (59°F to 86°F). Protect oral suspension from freezing.





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Price:10.00
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Company Description
Sundent Pharm Group
Address:ShanghaiShanghaiShanghaiSongjiangNo.1333 Xinlong Road, Shanghai.China.
Descption:Sundent Pharm Group (together with its subsidiaries, the Groupâ€) is one of the largest comprehensive manufacturing, marketing, promotion and channel management service provider dedicated to pharmaceutical products.? Since establishment in 2004, the Group has determined to apply global vision to local management, and has introduced a series of pharmaceutical products embedded with technologies that represent international advanced level to China, South America, Eastern European and south Asia countries.? As of Dec 2015, the company had portfolio of pharmaceutical products, covering pain management, cardiovascular, respiratory, gastroenterology, immunology and other therapeutic areas.? At the same time, the Group endeavors to uplift the market value of these brands.

With a global horizon and well-deserved creditability in international market development, the Group has established long-term and stable cooperation with a number of renowned Chinese pharmaceutical manufacturer leaders, independent product quality analysis and develop centers, Chinese SFDA etc., The network lays the foundation of the sustainable development of the company through the comprehensive and effective products introduction and cooperation.

Looking into the future, the Group is committed to build itself into a cutting-edge pharmaceutical manufacturing and marketing group company that grasps the sales channel and product pricing advantage in mainland China. We believe that, with rapid development of China's pharmaceutical industry, through an open-minded attitude, perspective new product introduction capability, accurate product marketing strategy, comprehensive marketing network and effective management system, Sundent Pharmaceutical Group is able to achieve our development target.
Registered Capital:50
EmployeeNum:50
Sundent Pharm Group
Contact:Tracy zhang
Telphone:86-21-67897115-0
Fax:86-21-67897115-802
Email:Sundent@aliyun.com
Company Website:[Misafirler Kayıt Olmadan Link Göremezler Lütfen Kayıt İçin Tıklayın ! ]